کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1176808 961882 2006 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Determination of compound aminopyrine phenacetin tablets by using artificial neural networks combined with principal components analysis
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آنالیزی یا شیمی تجزیه
پیش نمایش صفحه اول مقاله
Determination of compound aminopyrine phenacetin tablets by using artificial neural networks combined with principal components analysis
چکیده انگلیسی
A method for simultaneous, nondestructive analysis of aminopyrine and phenacetin in compound aminopyrine phenacetin tablets with different concentrations has been developed by principal component artificial neural networks (PC-ANNs) on near-infrared (NIR) spectroscopy. In PC-ANN models, the spectral data were initially analyzed by principal component analysis. Then the scores of the principal components were chosen as input nodes for the input layer instead of the spectral data. The artificial neural network models using the spectral data as input nodes were also established and compared with the PC-ANN models. Four different preprocessing methods (first-derivative, second-derivative, standard normal variate (SNV), and multiplicative scatter correction) were applied to three sets of NIR spectra of compound aminopyrine phenacetin tablets. The PC-ANNs approach with SNV preprocessing spectra was found to provide the best results. The degree of approximation was performed as the selective criterion of the optimum network parameters.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Analytical Biochemistry - Volume 351, Issue 2, 15 April 2006, Pages 174-180
نویسندگان
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