Mass spectrometry analysis of metals, other elements and lipids in urine samples of Fabry disease patients

► ICP-MS method allows metal/other elements quantification in urine of Fabry patients. ► Correlations were established for metals/other elements versus lipids in Fabry disease. ► Urinary strontium values were lower in all male Fabry patients under study. ► Urinary barium levels were lower in all controls. ► Mass spec allows quantitative analysis of urinary isotopes versus Fabry disease biomarkers.