کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
11964 769 2005 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Biomaterial microarrays: rapid, microscale screening of polymer–cell interaction
موضوعات مرتبط
مهندسی و علوم پایه مهندسی شیمی بیو مهندسی (مهندسی زیستی)
پیش نمایش صفحه اول مقاله
Biomaterial microarrays: rapid, microscale screening of polymer–cell interaction
چکیده انگلیسی

The identification of biomaterials that induce optimal gene expression patterns and allow for appropriate levels of cellular attachment is of central importance in tissue engineering and cell therapy. Herein, we describe the creation of cell-compatible, biomaterial microarrays, that allow rapid, microscale testing of biomaterial interactions with cells. As proof of principle, we simultaneously characterized over 3456 human mesenchymal stem cell (hMSC)–biomaterial composite interactions, and describe preliminary studies on the utility of these arrays with a neural stem cell line (NSC), and primary articular chondrocytes.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Biomaterials - Volume 26, Issue 23, August 2005, Pages 4892–4897
نویسندگان
, , , , ,