کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1251088 970885 2008 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
First Total Synthesis of Hyacinthacine A6 from the Protected Derivative of Polyhydroxylated Pyrrolidine
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی (عمومی)
پیش نمایش صفحه اول مقاله
First Total Synthesis of Hyacinthacine A6 from the Protected Derivative of Polyhydroxylated Pyrrolidine
چکیده انگلیسی
(1S,2R,3R,5R,7aR)-1,2-Dihydroxy-3-hydroxymethyl-5-methylpyrrolizidine(hyacinthacine A6, 1) was synthesized by Wittig's methodology via the reaction of aldehyde 6, prepared from the partially protected derivative of polyhydroxylated pyrrolidine, with appropriated ylides, followed by cyclization through the internal reductive amination process of the resulting α,β-unsaturated ketone 7, and total deprotection.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Chemical Research in Chinese Universities - Volume 24, Issue 4, July 2008, Pages 469-472
نویسندگان
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