کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1251192 | 1496053 | 2012 | 6 صفحه PDF | دانلود رایگان |

Novel styrenic Schiff base derivatives of benzothiazole are synthesized. The condensation of 4-vinylbenzaldehyde 1 with either benzothiazol-2-amine or 4-methoxy-benzothiazol-2-amine leads to a mixture of two isomers. From 4-methyl-benzothiazol-2-amine and 6-fluoro-benzothiazol-2-amine, the N-(4-vinylbenzylidene)-4-methyl-benzothiazol-2-amine 8 and N-(4-vinylbenzylidene)-6-fluoro-benzothiazol-2-amine 9 are isolated, respectively. The structures of the synthesized Schiff bases are confirmed through a combination of various spectroscopic techniques including IR, UV, 1H and 13C NMR. A kinetic study of the hydrolysis process of derivatives 6 and 9 in buffered aqueous medium at pH 4.4, 7.4 and 8.5 is conducted by UV spectroscopy. It is shown that the hydrolysis of these compounds is a first order reaction showing an increasing rate as the medium acidity is enhanced.
Journal: Arabian Journal of Chemistry - Volume 5, Issue 2, April 2012, Pages 245–250