Total synthesis of norleucosceptroids F and G

First total synthesis of norleucosceptroids F and G has been achieved through key steps of Michael–Aldol cascade, oxa-Michael cyclization–dehydration–deprotection cascade and cross metathesis (CM), this work developed a general and concise method to the synthesis of leucosceptroid and norleucosceptroid.

We accomplished total synthesis of norleucosceptroids F and G through eight and nine steps, respectively.Figure optionsDownload as PowerPoint slide