Nickel oxide nanoparticles catalyzed synthesis of poly-substituted quinolines via Friedlander hetero-annulation reaction

Reusable acidic nickel oxide nanoparticles have been synthesized, characterized and applied as a catalyst to convert 2-aminoaryl ketones and β-ketoesters/ketones into the corresponding quinolines in good yields with high selectivity. This could serve as a simple and convenient procedure for the Friedlander annulations.

Reusable acidic nickel oxide nanoparticles have been synthesized, characterized and used as a catalyst to convert 2-aminoaryl ketones and β-ketoesters/ketones into the corresponding quinolines.Figure optionsDownload as PowerPoint slide