Tandem synthesis of functionalized hexaalkyl benzoisoquinolinopyrrolonaphthyridine-hexacarboxylate, via isoquinoline based multi-component reaction

An expedient, synthetic method to fused polycyclic derivatives of isoquinoline is described via tandem reaction of isoquinoline, dialkyl acetylenedicarboxylates and dialkyl chloromalonate.

An expedient, synthetic method to fused polycyclic derivatives of isoquinoline is described via tandem reaction of isoquinoline, dialkyl acetylenedicarboxylates and dialkyl chloromalonate.Figure optionsDownload as PowerPoint slide