کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1254274 | 971365 | 2013 | 4 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Synthesis and BK channel-opening activity of novel N-acylhydrazone derivatives from dehydroabietic acid
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی (عمومی)
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
A series of hydrazone and N-acylhydrazone derivatives of dehydroabietic acid were synthesized and evaluated for BK channel-opening activities in an assay system of CHO-K1 cells expressing hBKα channels. The assay results indicated that the activities of the investigated compounds were influenced by the physicochemical properties of the substituent at hydrazone moiety.
A series of hydrazone (2) and N-acylhydrazone derivatives (3) of dehydroabietic acid were synthesized and evaluated for BK channel opening activities in an assay system of CHO-K1 cells expressing hBKα channels.Figure optionsDownload as PowerPoint slide
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Chinese Chemical Letters - Volume 24, Issue 11, November 2013, Pages 1023–1026
Journal: Chinese Chemical Letters - Volume 24, Issue 11, November 2013, Pages 1023–1026
نویسندگان
Xia-Shi Lv, Yong-Mei Cui, He-Yun Wang, Hai-Xia Lin, Wei-Ya Ni, Tomohiko Ohwada, Katsutoshi Ido, Kohei Sawada,