Synthesis of quinazolinones from o-aminobenzamides and benzyl amines under metal-free conditions

A convenient and transition-metal free protocol for quinazolinones synthesis with o-aminobenzamides and benzyl amines as substrates has been developed. Using H2O2 as the oxidant, various quinazolinones were obtained in moderate to good yields under metal- and additive-free conditions.

A convenient and transition-metal free protocol for quinazolinones synthesis with o-aminobenzamides and benzyl amines as substrates has been developed. Using H2O2 as the oxidant, various quinazolinones were obtained in moderate to good yields.Figure optionsDownload as PowerPoint slide