کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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1254719 | 971387 | 2014 | 4 صفحه PDF | دانلود رایگان |
With the increase of herbicide-resistant weeds, novel, more selective and even more potent herbicides to control weeds are needed. In this paper, a series of N-fluorinated phenyl-N′-pyrimidyl urea derivatives were synthesized and screened for their herbicidal activities against Amaranthus retroflexus (AR) and Setaria viridis (SV). Compound 25 (N-(3-trifluoromethylphenyl)-N′-(2-amino-4-chloro-6-methylpyrimidyl) urea) exhibited marked herbicidal activity against SV (IC50 = 11.67 mg/L) and is more potent than bensulfuron (IC50 = 27.45 mg/L), a commercially available herbicide. A statistically significant CoMFA model with high prediction abilities (q2 = 0.869, r2 = 0.989) was obtained.
A series of N-fluorine-containing phenyl-N′-pyrimidylurea derivatives were synthesized. Compound 25 (N-(3-trifluoromethylphenyl)-N′-(2-amino-4-chloro-6-methylpyrimidyl) urea) exhibited marked herbicidal activity against Setaria viridis (SV) (IC50 = 11.67 mg/L) and was more potent than bensulfuron (IC50 = 27.45 mg/L), a commercially available herbicide. A statistically significant CoMFA model with high predict abilities (q2 = 0.869, r2 = 0.989) were obtained.Figure optionsDownload as PowerPoint slide
Journal: Chinese Chemical Letters - Volume 25, Issue 7, July 2014, Pages 1069–1072