کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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1254899 | 971397 | 2013 | 4 صفحه PDF | دانلود رایگان |

An efficient and facile method for the synthesis of N-substituted pyrroles in moderate to good yields by the Paal–Knorr reaction of γ-diketones with amines in the presence of β-cyclodextrin in aqueous media has been developed. Moreover, this process tolerated diamines (e.g., para-, meta- or ortho-phenylenediamine) to construct bis-pyrrole or mono-pyrrole derivates. β-Cyclodextrin can be recovered easily after the reactions and reused without evident loss in activity.
An efficient and facile method for the synthesis of N-substituted pyrroles by the Paal–Knorr reaction of γ-diketones with amines in the presence of β-cyclodextrin in aqueous media has been developed. This process tolerated diamines (e.g., para-, meta- or ortho-phenylenediamine) to construct bis-pyrrole or mono-pyrrole derivates.Figure optionsDownload as PowerPoint slide
Journal: Chinese Chemical Letters - Volume 24, Issue 9, September 2013, Pages 793–796