کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1254902 | 971397 | 2013 | 5 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Three component reactions: An efficient and green synthesis of 3,4-dihydropyrimidin-2-(1H)-ones and thiones using silica gel-supported l-pyrrolidine-2-carboxylic acid-4-hydrogen sulfate
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی (عمومی)
پیش نمایش صفحه اول مقاله

چکیده انگلیسی
An environmentally benign aqueous protocol for the synthesis of 3,4-dihydropyrimidin-2-(1H)-ones and thiones promoted by a green catalyst, silica gel-supported l-pyrrolidine-2-carboxylic acid-4-hydrogen sulfate, has been developed. The use of nontoxic, thermally stable and inexpensive amino acid catalyst makes the process simple with minimal amount of chemical waste. Compared with classical Biginelli reaction conditions, this new method has the advantages of high yields and simple workup procedures.
Silica gel-supported l-pyrrolidine-2-carboxylic acid-4-hydrogen sulfate as a green organocatalyst has been introduced for the synthesis of 3,4-dihydropyrimidin-2-(1H)-ones and thiones.Figure optionsDownload as PowerPoint slide
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Chinese Chemical Letters - Volume 24, Issue 9, September 2013, Pages 804–808
Journal: Chinese Chemical Letters - Volume 24, Issue 9, September 2013, Pages 804–808
نویسندگان
Arash Ghorbani-Choghamarani, Parisa Zamani,