کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1254926 | 971400 | 2010 | 4 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Design, synthesis and anti-proliferative studies of a novel series of indirubin derivatives
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی (عمومی)
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Design, synthesis and anti-proliferative studies of a novel series of indirubin derivatives Design, synthesis and anti-proliferative studies of a novel series of indirubin derivatives](/preview/png/1254926.png)
چکیده انگلیسی
A series of novel derivatives of indirubin were synthesized and evaluated for their anti-proliferative activity against human cancer cell lines of SGC7901, A549, HL-60, SK-BR-3 and HCT116. Most of the compounds displayed more potent activity than Sunitinib. In addition, the derivatives showed improved water solubility, which may be favorable to their pharmacokinetic performances.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Chinese Chemical Letters - Volume 21, Issue 12, December 2010, Pages 1407–1410
Journal: Chinese Chemical Letters - Volume 21, Issue 12, December 2010, Pages 1407–1410
نویسندگان
Tian Cai Wang, Ju Zhi Wei, Chuan Sheng Guo, Hui Bin Zhang, Hou Xing Fan,