A predictive, simple and rapid method for thermodynamic study on the binding of copper ion with Alzheimer's amyloid β peptide

The interaction of CuCl2 to the first 16 residues of the Alzheimer's amyliod β peptide, Aβ(1–16) was studied by isothermal titration calorimetry at pH 7.2 and 37 °C in aqueous solution.