Efficient and convenient preparation of N-tosylimines catalyzed by indium trichloride

A new method for preparation of N-tosylimines by InCl3-mediated condensation of aldehydes with p-toluenesulfonamide in refluxing benzene is reported. The procedure is lauded by its simplicity, mild reaction conditions, excellent yields and adaptability to electron deficient and electron rich aromatic, and α,β-unsaturated aldehydes.