Two new 5α-adynerin-type compounds from Parepigynum funingense

A new 5α-adynerin-type cardenolide, named funingenoside U (1), together with its aglycone, (17R)-3β-hydroxy-4β-acetoxy-8, 14β-epoxy-5α-card-20(22)-enolide, was isolated from the roots of Parepigynum funingense. Their structures were established on the basis of spectral (MS, 1D and 2D NMR) measurements and chemical evidences.