کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1256784 | 971529 | 2015 | 5 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: Convenient synthesis of spiro[indoline-3,4′-pyrano[2,3-c]pyrazole] and spiro[acenaphthyl-3,4′-pyrano[2,3-c]pyrazoles] via four-component reaction Convenient synthesis of spiro[indoline-3,4′-pyrano[2,3-c]pyrazole] and spiro[acenaphthyl-3,4′-pyrano[2,3-c]pyrazoles] via four-component reaction](/preview/png/1256784.png)
The domino four-component reaction of hydrated hydrazine, dimethyl acetylenedicarboxylate, isatin and malononitrile or ethyl cycanoacetate in ethanol in the presence of triethylamine afforded the polysubstituted spiro[indoline-3,4′-pyrano[2,3-c]pyrazole] derivatives in satisfactory yields. Under similar conditions, the four-component reaction containing acenaphthenequinone also resulted in the spiro[acenaphthyl-3,4′-pyrano[2,3-c]pyrazole] in good yields.
The base promoted four-component reaction of hydrated hydrazine, dimethyl acetylenedicarboxylate, isatines and malononitrile (ethyl cycanoacetate) in ethanol afforded polysubstituted spiro[indoline-3,4′-pyrano[2,3-c]pyrazoles] and spiro[acenaphthyl-3,4′-pyrano[2,3-c]pyrazoles].Figure optionsDownload as PowerPoint slide
Journal: Chinese Chemical Letters - Volume 26, Issue 7, July 2015, Pages 889–893