An efficient synthesis of imidodicarbonic diamides from 1,3-thiazetidin-2-ones with NH2OH·HCl via ring-opening reaction

A ring-opening process of 4-imino-1,3-thiazetidin-2-ones with NH2OH·HCl was described for the first time. Two different scaffolds of imidodicarbonic diamide were obtained selectively in good yields in the presence of organic base. The obtained imidodicarbonic diamides were demonstrated by X-ray diffraction analysis.

A ring-opening process of 4-imino-1,3-thiazetidin-2-ones with NH2OH·HCl was described for the first time. Two different scaffolds of imidodicarbonic diamide were obtained selectively in good yields in the presence of organic base. The obtained imidodicarbonic diamides were demonstrated by X-ray diffraction analysis.Figure optionsDownload as PowerPoint slide