کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1257206 | 971551 | 2015 | 4 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Synthesis and bio-evaluation of phenothiazine derivatives as new anti-tuberculosis agents
ترجمه فارسی عنوان
سنتز و ارزیابی زیستی مشتقات فنوتیازین به عنوان عوامل جدید ضد سل
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موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی (عمومی)
چکیده انگلیسی
Two series of phenothiazine derivatives were designed and synthesized. All compounds were tested for anti-tuberculosis activities against Mycobacterium tuberculosis H37RV. In comparison with mother compound of chlorpromazine, compound 6e shows promising anti-tuberculosis activity and much less mammalian cell cytotoxicity, compound 6e merits to be further explored as new anti-tuberculosis agents.
Two series of phenothiazine derivatives were designed and synthesized. They were evaluated for anti-tuberculosis activity.Figure optionsDownload as PowerPoint slide
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Chinese Chemical Letters - Volume 26, Issue 8, August 2015, Pages 951–954
Journal: Chinese Chemical Letters - Volume 26, Issue 8, August 2015, Pages 951–954
نویسندگان
Chun-Xian He, Hui Meng, Xiang Zhang, Hua-Qing Cui, Da-Li Yin,