1-Sulfopyridinium chloride: Green and expeditious ionic liquid for the one-pot synthesis of fused 3,4-dihydropyrimidin-2(1H)-ones and thiones under solvent-free conditions

1-Sulfopyridinium chloride portrayed as an efficient and recyclable ionic liquid for the synthesis of fused 3,4-dihydropyrimidin-2(1H)-ones and thiones via a modified Biginelli reaction involving one-pot three component condensation of 6-methoxy-1-tetralone, arylaldehydes and urea/thiourea under solvent-free conditions. Analytically pure products are formed within 10–20 min in excellent yields.

1-Sulfopyridinium chloride portrayed as an efficient and recyclable ionic liquid for the synthesis of fused 3,4-dihydropyrimidin-2(1H)-ones and thiones via a modified Biginelli reaction under solvent-free conditions.Figure optionsDownload as PowerPoint slide