Supramolecular synthesis of 3,4-dihydropyrimidine-2(1H)-one/thiones under neat conditions

An efficient solvent free method for the synthesis of various 3,4-dihydropyrimidin-2(1H)-one/thiones in excellent yields using sulfonated β-cyclodextrine as recyclable catalyst is described. Sulfonated β-cyclodextrine was found to be efficient, recyclable heterogeneous catalyst and showed rate enhancements, high yields and short reaction times in this transformation.