کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1257798 971580 2011 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
A novel hydrophilic polystyrene-based beads for hydrophilic interaction chromatography by surface-initiated atom transfer radical polymerization
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی (عمومی)
پیش نمایش صفحه اول مقاله
A novel hydrophilic polystyrene-based beads for hydrophilic interaction chromatography by surface-initiated atom transfer radical polymerization
چکیده انگلیسی

A one-step procedure to hydrophilize monodisperse poly (chloromethyl-styrene-co-divinylbenzene) beads has been presented with 2-hydroxy-3-[4-(hydroxymethyl)-1H-1,2,3-triazol-1-yl] propyl 2-methylacrylate (HTMA) as monomer by surface-initiated atom transfer radical polymerization (SI-ATRP). The length of the grafted poly (HTMA) chain was varied via controlling the ratio of HTMA to initiator on the surface of the beads. Using these grafted beads as the stationary phase in hydrophilic interaction chromatography, good separation was obtained for nucleosides in the mobile phase of acetonitrile-water. It was also found that the retention time and selectivity of solutes showed a positive relationship with the length of the grafted poly (HTMA) chain.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Chinese Chemical Letters - Volume 22, Issue 2, February 2011, Pages 245–248
نویسندگان
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