Synthetic derivatives of spiromesifen and their bioactivity research

Sixteen new derivatives of spiromesifen were synthesized from 3-(2,4,6-trimethylphenyl)-4-hydroxy-Δ3-dihydrofuran-2-one. Their bioactivities against diamondbackmoth (Plutella xylostella) and spider mites (Tetranychus cinnabarinus) were also evaluated. The structures of these derivatives were confirmed by 1H NMR, MS.