کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1258053 971595 2010 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Synthesis and characterization of new biodegradable thermosensitive polyphosphazenes with lactic acid ester and methoxyethoxyethoxy side groups
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی (عمومی)
پیش نمایش صفحه اول مقاله
Synthesis and characterization of new biodegradable thermosensitive polyphosphazenes with lactic acid ester and methoxyethoxyethoxy side groups
چکیده انگلیسی

Two novel biodegradable thermosensitive polyphosphazenes with lactic acid ester and methoxyethoxyethoxy side groups were synthesized via the macromolecular substitution reactions of poly(dichlorophosphazene) with the sodium salt of lactic acid ester and sodium methoxyethoxyethoxide. Their structures were confirmed by 31P NMR, 1H NMR, 13C NMR, IR, DSC, and elemental analysis. The lower critical solution temperature (LCST) behavior in water and in vitro degradation property of the polymers was investigated. The results indicated that two polymers showed LCST phase transition over a range of concentrations from 0.13 to 15 wt% and pH-sensitive degradation properties.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Chinese Chemical Letters - Volume 21, Issue 2, February 2010, Pages 237–241
نویسندگان
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