کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1258300 | 971610 | 2008 | 4 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Preparation of thiophilic paramagnetic adsorbent for separation of antibodies
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی (عمومی)
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Preparation of thiophilic paramagnetic adsorbent for separation of antibodies Preparation of thiophilic paramagnetic adsorbent for separation of antibodies](/preview/png/1258300.png)
چکیده انگلیسی
The micron-sized microspheres with superparamagnetic property were synthesized with vinyl acetate and divinylbenzene by microsuspension polymerization. After the complete alcoholysis, these hydroxyl-functionalized microspheres were activated by divinylfone and modified with mercaptoethanol to prepare the thiophilic magnetic adsorbent, which was used to specifically isolate immunoglobulin G (IgG) from human serum. This thiophilic magnetic adsorbent performed an evident salt-dependent adsorption behavior for IgG. Due to their salt-promoted adsorption towards IgG under high salt concentration, the absorbed antibodies could be extracted in low salt concentration with high purity.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Chinese Chemical Letters - Volume 19, Issue 12, December 2008, Pages 1495–1498
Journal: Chinese Chemical Letters - Volume 19, Issue 12, December 2008, Pages 1495–1498
نویسندگان
Ming Qin Chen, Zhi Yong Lin, Hao Qian,