کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1266852 | 972304 | 2006 | 4 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Synthesis of N-(4-bromo-2-trifluoromethylphenyl)-1-(2-fluorophenyl)-O,O-dialkyl-α-aminophosphonates under ultrasonic irradiation
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی (عمومی)
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Synthesis of N-(4-bromo-2-trifluoromethylphenyl)-1-(2-fluorophenyl)-O,O-dialkyl-α-aminophosphonates under ultrasonic irradiation Synthesis of N-(4-bromo-2-trifluoromethylphenyl)-1-(2-fluorophenyl)-O,O-dialkyl-α-aminophosphonates under ultrasonic irradiation](/preview/png/1266852.png)
چکیده انگلیسی
Boron trifluoride diethyl etherate catalyzes the Mannich-type reaction of 2-trifluoromethyl-4-bromoaniline and O,O-dialkylphosphite with 2-fluorobenzoaldehyde under ultrasonic irradiation to synthesize the corresponding product α-aminophosphonate. The advantages of the procedure include short reaction period, high yield and simple working up. Their structures were clearly established by IR, 1H NMR, 13C NMR and elemental analysis. The bioassay tests showed that the title compounds exhibit moderate antitumor activity in vitro by MTT method.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Ultrasonics Sonochemistry - Volume 13, Issue 2, February 2006, Pages 139–142
Journal: Ultrasonics Sonochemistry - Volume 13, Issue 2, February 2006, Pages 139–142
نویسندگان
Bao-An Song, Guo-Ping Zhang, Song Yang, De-Yu Hu, Lin-Hong Jin,