کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1266977 | 972311 | 2011 | 6 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: Impact of ultrasound-assisted extraction on quality and photostability of the Pothomorphe umbellata extracts Impact of ultrasound-assisted extraction on quality and photostability of the Pothomorphe umbellata extracts](/preview/png/1266977.png)
Pothomorphe umbellata (L.) Miq. is a Brazilian shrub with therapeutic and economic applications. There are some reports on the technological development of P. umbellata preparations; however, there are no studies on the influence of non-conventional extraction procedures on the quality of P. umbellata extracts. The aim of this study was to evaluate the effects of the ultrasound-assisted extraction (UE) parameters upon the extraction yield (EY%) of 4-nerolidylcatechol (4-NC) and the antioxidant activity of P. umbellata extracts using a factorial design and response surface methodology. Extracts obtained by UE and percolation were compared, and the photostability of 4-NC was evaluated via the exposure of UVA and visible light to the samples. The most influential variables observed for the UE were the ethanol-to-water and drug-to-solvent ratios. UE improved the extraction kinetics of 4-NC from plant material and improved the antioxidant activity of the extracts. Some of the ultrasound extracts showed an antioxidant activity that was not proportional to their 4-NC concentration, which suggests the presence of other active antioxidant compounds in these P. umbellata extracts. There was no significant difference in the photostability of 4-NC between the percolated and ultrasound extracts. Surprisingly, the isolated 4-NC material was significantly more stable when exposed to UVA-visible light compared to 4-NC in the plant extracts.
► Ultrasound methods improved the antioxidant activity of Pothomorphe umbellata samples.
► Ultrasound extracted other active compounds and preserved their chemical integrity.
► The drug-to-solvent ratio affected the extraction yield in the ultrasound extraction.
► The ethanol concentration determined the activity of the ultrasound extracts.
► The photostability of 4-NC was lower in plant extracts than in the isolated form.
Journal: Ultrasonics Sonochemistry - Volume 18, Issue 5, September 2011, Pages 1002–1007