Synthesis, characterization and antimicrobial activity of new cobalt (II), nickel (II) and copper (II) complexes with 2-(2-hydroxy-1, 2-diphenylethylideneamino) benzoic acid

The new Schiff base ligand 2-(2-hydroxy-1, 2-diphenylethylideneamino) benzoic acid [HL] and its Co(II), Ni(II) and Cu(II) metal complexes were synthesized. The ligand and metal complexes were characterized by elemental analysis, UV-visible, IR, 1H NMR spectroscopy, thermal studies and magnetic susceptibility measurement. The ligand [HL] was synthesized by condensation of benzoin and 2-amino benzoic acid. On the basis of electronic spectral data and magnetic susceptibility measurement the octahedral geometry has been proposed for Cu(II), Ni(II) and Co(II) complexes. The ligand and metal (II) complexes were also screened for their antimicrobial activity against microorganisms Staphylococcus aureus and Pseudomonas aeruginosa and antifungal activity against the fungi Candida albicans and Aspergillus niger.

Graphical Abstract2-(2-Hydroxy 1,2-dipheylethylideneamino) benzoic acid (HL) and its Cu(II), Co(II) and Ni(II) complexes were synthesized and characterized on the basis of Elemental analysis, IR, UV–visible,1H NMR, spectral studies, magnetic susceptibility, thermal analysis. The ligand and its Cu(II), Ni(II) and Co(II) complexes were screened for their antibacterial and antifungal activity by using minimum inhibitory concentrations (MICs) method.Figure optionsDownload as PowerPoint slideResearch Highlights
► Synthesis, characterization and antimicrobial activity of new cobalt (II), nickel (II) and copper (II) complexes with 2-(2-hydroxy-1, 2-diphenylethylideneamino) benzoic acid.
► 2-(2-Hydroxy 1,2-dipheylethylideneamino) benzoic acid (HL) and its Cu(II), Co(II) and Ni(II) complexes were synthesized and characterized on the basis of Elemental analysis, IR, UV–visible,1H NMR, spectral 23 studies, magnetic susceptibility, thermal analysis.
► The ligand and its Cu (II), Ni (II) and Co (II) complexes were screened for their antibacterial and antifungal activity by using minimum inhibitory concentrations (MICs) method.