A reusable polymer supported copper(I) complex for the C–N bond cross-coupling reaction

The Ullmann coupling of amines with aryl iodide as well as arylboronic acids and N(H)-heterocycles with arylboronic acids has been carried out efficiently using PS-LCu(I) catalyst. The copper complex has been prepared and characterized by using scanning electron microscope (SEM), elemental analysis, atomic absorption spectroscopy (AAS), Thermo gravimetric analysis and spectrometric methods like Fourier transform infrared spectroscopy (FTIR). The effects of various parameters such as temperature, solvent and base on the reaction system were studied. The reusability experiments show that the catalyst can be used five times without much loss in the catalytic activity.

The Ullmann coupling of amines with aryl iodide as well as arylboronic acids and N(H)-heterocycles with arylboronic acids have been carried out efficiently using polymer supported Cu(I) complex. The effects of various parameters were studied. The reusability experiments show that the catalyst can be reused five times.Figure optionsDownload as PowerPoint slideResearch highlights
► Copper complex was synthesized from macroporous chloromethylated polystyrene.
► This catalyst shows excellent catalytic activity in N-arylation reaction.
► This catalyst shows excellent catalytic activity in amination reactions.