Synthesis and characterization of water soluble choline labeled cadmium selenide/zinc selenide/zinc sulfide luminescent quantum dots

• Synthesis of unique choline- labeled CdSe/ZnSe/ZnS core-shell quantum dots.
• Solubilization in aqueous solution for biological applications.
• Exhibits strong luminescence in aqueous solution.

Water soluble choline-labeled CdSe/ZnSe/ZnS quantum dot (QD) bioconjugates were synthesized by attaching a thiolated choline analogue to the core-shell QD surface. Characterization was conducted by absorption and luminescence spectroscopy and scanning electron microscopy. QDs with diameters of 5–6 nm resulted and exhibited a luminescence maximum at 663 nm in aqueous solution.

Water soluble choline- labeled CdSe/ZnSe/ZnS core-shell quantum dots were synthesized and exhibit strong luminescence in aqueous solution.Figure optionsDownload as PowerPoint slide