کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1313614 1499329 2015 9 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Copper(0)-mediated fluoroalkylation of iodobenzene with 2-bromo-1,1,2,2-tetrafluoroethyl compounds: Investigation on the influence of R substituent on the reactivity of RCF2Cu species
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی معدنی
پیش نمایش صفحه اول مقاله
Copper(0)-mediated fluoroalkylation of iodobenzene with 2-bromo-1,1,2,2-tetrafluoroethyl compounds: Investigation on the influence of R substituent on the reactivity of RCF2Cu species
چکیده انگلیسی


• The copper(0)-mediated reaction between aryl iodides and 2-bromo-1,1,2,2-tetrafluoroethyl compounds has been investigated.
• A general method for the synthesis of tetrafluoroethylene-containing compounds has been developed.
• A comparison with other fluoroalkylation reactions disclosed the crucial role of R on the reactivity of RCF2Cu species.

We have made a systematic investigation on the copper(0)-mediated tetrafluoroethylenation of iodobenzene with structurally diverse 2-bromo-1,1,2,2-tetrafluoroethyl compounds. A comparison of this reaction with 1,2,2-trifluoro-1-phenylethylation and the known functionalized difluoroalkylation demonstrates that the substituent R of α,α-difluoroalkyl copper species RCF2Cu plays a crucial role on their reactivity, which is believed to be useful for the development of new fluoroalkylation reactions under the promotion of transition metals.

Figure optionsDownload as PowerPoint slide

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Fluorine Chemistry - Volume 171, March 2015, Pages 139–147
نویسندگان
, , , ,