کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1313690 | 1499356 | 2012 | 6 صفحه PDF | دانلود رایگان |
Novel SO3H-functionalized ionic liquids were successfully applied as catalysts for one-pot Fischer indole synthesis under microwave irradiation and in a water medium. Various types of indoles were prepared using single-carbonyl ketones/aldehydes or cyclohexandiones with aryhydrazine hydrochlorides in 86–96% yields in water under microwave irradiation. The indole products could be conveniently separated from the reaction mixture through filtration, and the catalytic system of [(HSO3-p)2im][CF3SO3]/H2O could be reused directly without any treatment. The entire process is simple, time saving, and environmentally friendly.
Novel SO3H-functionalized ionic liquids were successfully applied as catalysts for one-pot Fischer indole synthesis under microwave irradiation and in a water medium. Various types of indoles were prepared using single-carbonyl ketones/aldehydes or cyclohexandiones with aryhydrazine hydrochlorides in 86–96% yields in water under microwave irradiation. The entire process is simple, time saving, and environmentally friendly.Figure optionsDownload as PowerPoint slideHighlights
► The whole process was performed in water without using any organic solvents.
► The reaction–separation–recycle process was quite convenient.
► The catalytic system of [(HSO3-p)2im][CF3SO3]/H2O could be reused directly.
Journal: Journal of Fluorine Chemistry - Volume 144, December 2012, Pages 45–50