کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1313908 | 1499357 | 2012 | 7 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: Reactions of 4-substituted tetrafluoropyridine derivatives with sulfur nucleophiles: SNAr and annelation processes Reactions of 4-substituted tetrafluoropyridine derivatives with sulfur nucleophiles: SNAr and annelation processes](/preview/png/1313908.png)
Reactions of model sulfur centred nucleophiles with 4-nitro-, 4-phenylsulfonyl- and 4-cyano-tetrafluoropyridine gave products arising from substitution of the nitro- and sulfonyl substituent or ring fluorine respectively. Ring fused products are formed upon reaction of 4-cyano-tetrafluoropyridine with mercapto-acetic acid ethyl ester.
Reactions of sulfur centred nucleophiles with tetrafluoropyridine derivatives gave substitution or ring-fused products arising from displacement of the 4-substituent or ring fluorine.Figure optionsDownload as PowerPoint slideHighlights
► 4-Tetrafluoropyridine derivatives react with sulfur nucleophiles.
► Ipso substitution of 4-nitro and 4-phenylsulfonyl substituents occur.
► Thieno[2,3-c]pyridine products formed from 4-cyano-tetrafluoropyridine.
Journal: Journal of Fluorine Chemistry - Volume 143, November 2012, Pages 148–154