کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1313992 1499335 2014 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Direct palladium-catalyzed desulfitative CC coupling of polyfluoroarenes with arylsulfinate salts: Water-accelerated reactions
ترجمه فارسی عنوان
ترکیب کلاسیک سولفیتی با کاتالیزوری مستقیم پلی فلوآرآرنها با نمکهای آریل سولفنات پتاسیم مستقیم: واکنش سریع آب
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی معدنی
چکیده انگلیسی


• A direct Pd-catalyzed desulfitative cross-coupling of polyfluoroarenes with various arylsulfinate salts to afford fluorinated biaryls has been described.
• This reaction was accelerated by trace amount of water.
• Several functional groups are compatible with this reaction.

A new approach to the synthesis of fluorinated biaryl compounds from easily available starting materials is described. This protocol is based on the direct palladium-catalyzed desulfitative cross-coupling of polyfluoroarenes with various arylsulfinate salts via CH bond activation, accelerated by trace amount of water. The method allows the synthesis of various fluorinated biaryl products in moderate to good yields, and tolerated a variety of functional groups, including alkyl, phenyl, methoxy, fluoro, and chloro groups.

A new approach to the synthesis of fluorinated biaryl compounds from easily available starting materials is described. This protocol is based on the direct palladium-catalyzed desulfitative cross-coupling of polyfluoroarenes with various arylsulfinate salts via CH bond activation, accelerated by trace amount of water. The method allows the synthesis of various fluorinated biaryl products in moderate to good yields, and tolerated a variety of functional groups, including alkyl, phenyl, methoxy, fluoro, chloro, and nitro groups.Figure optionsDownload as PowerPoint slide

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Fluorine Chemistry - Volume 165, September 2014, Pages 76–80
نویسندگان
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