کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1314096 | 1499366 | 2012 | 4 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: Catalytic fluorination of dichloromethylbenzene by HF in liquid phase. Preparation of fluorinated building blocks Catalytic fluorination of dichloromethylbenzene by HF in liquid phase. Preparation of fluorinated building blocks](/preview/png/1314096.png)
The selective fluorination by successive Cl/F exchanges of the dichloromethylbenzene, was studied in the presence of HF as the fluorinating agent. The influence of the presence of a catalyst or a basic solvent (such as dioxane, pyridine, tributylphosphate) in order to favour the fluorination was investigated. In mild conditions, (50 °C and after 1 h of reaction), the fluorination of the dichloromethylbenzene was observed and the polymerization reaction inhibited. The best results were obtained in the presence of the HF-dioxane system and antimony trifluoride as catalyst.
The selective fluorination by successive Cl/F exchanges of the dichloromethylbenzene, was studied in the presence of HF as the fluorinating agent. The influence of the presence of a catalyst or a basic solvent (such as dioxane, pyridine, tributylphosphate) in order to favour the fluorination was investigated.Figure optionsDownload as PowerPoint slideHighlights
► Two reaction in competition for the transformation of the dichloromethylbenzene.
► Fluorination reaction favored in the presence of HF-base system.
► Increase of the fluorination in the presence of the catalytic system HF-base-SbF3.
Journal: Journal of Fluorine Chemistry - Volume 134, February 2012, Pages 103–106