کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1314962 | 975995 | 2011 | 5 صفحه PDF | دانلود رایگان |
A l-proline catalyzed condensation–cyclization tandem process is reported, which affords the potentially pharmaceutic coumarin derivatives. The mild conditions, simplicity of the purification process and satisfactory yields makes the method a facile and effective way toward the 3-polyfluoroalkanesulfonyl coumarins.
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► A l-proline catalyzed condensation–cyclization tandem process is reported.
► The reaction gave the potentially pharmaceutic coumarin derivatives in good yields.
► The mild condition, simplicity of the purification process and satisfactory yields makes the method a facile and effective way toward the 3-polyfluoroalkanesulfonyl coumarins.
► And a possible reaction pathway was proposed.
Journal: Journal of Fluorine Chemistry - Volume 132, Issue 6, June 2011, Pages 409–413