کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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1336249 | 1500223 | 2016 | 9 صفحه PDF | دانلود رایگان |
The in-situ deprotonation of N-heterocyclic carbene (NHC) in the reaction of bis-benzimidazolium bromide salts (1a–6a) with Ag2O, yielded the formation of six dinuclear silver(I)–NHC complexes [Ag2(L)2]·2PF6 (7–12) (where L = 1–6: 3,3-(butane-1,4-diyl)-1,1-(2′/3′/4′-methylbenzyl/methylbenzonitrile)bisbenzimidazolium). Bis-benzimidazolium hexafluorophosphate salts (1b–6b) and complexes 7–12 were characterized using 1H and 13C NMR spectroscopy, FTIR spectroscopy and elemental analysis technique. Additionally, complex 12 was structurally characterized by single crystal X-ray diffraction technique. Antibacterial studies of these compounds against the Gram-negative bacteria Escherichia coli (ATCC 25922) and the Gram-positive bacteria Staphylococcus aureus (ATCC 12600) proved all the Ag(I)–NHC complexes exhibit antibacterial activities while all the bis-benzimidazolium salts showed negative result.
Six dinuclear silver(I)–NHC complexes [Ag2(L)2]·2PF6 (7–12) were successfully synthesized in relatively good yield by the in-situ deprotonation reaction of respective bis-benzimidazolium bromide salts (1a–6a) with Ag2O (where L = 1–6: 3,3-(butane-1,4-diyl)-1,1-(2′/3′/4′-methylbenzyl/methylbenzonitrile)bisbenzimidazolium). Bis-benzimidazolium hexafluorophosphate salts (1b–6b) and complexes 7–12 were characterized using 1H and 13C NMR spectroscopy, FTIR spectroscopy and elemental analysis technique. Additionally, complex 12 was structurally characterized by single crystal X-ray diffraction technique. Antibacterial studies of these compounds against the Gram-negative bacteria Escherichia coli (ATCC 25922) and the Gram-positive bacteria Staphylococcus aureus (ATCC 12600) proved all the Ag(I)–NHC complexes exhibit antibacterial activities while all the bis-benzimidazolium salts showed negative result.Figure optionsDownload as PowerPoint slide
Journal: Polyhedron - Volume 117, 15 October 2016, Pages 628–636