کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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1338279 | 979663 | 2007 | 8 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: 1H, 13C, 195Pt NMR study on platinum(II) interaction with sulphur containing Amadori compounds 1H, 13C, 195Pt NMR study on platinum(II) interaction with sulphur containing Amadori compounds](/preview/png/1338279.png)
The NMR study on the interaction of Pt(II) with Amadori compounds is performed. The Amadori compounds are derived from the reaction of β-d-glucose with l-cystine leading to N,N′-di-(1-deoxy-β-fructos-1-yl)-l-cystine [FruCyscys], and with l-methionine leading to N-(1-deoxy-β-fructos-1-yl)-l-methionine [FruMet].The great instability of 2-(1,2,3,4,5-pentahydroxypentyl)-1,3-thiazolidine-4-carboxylic acid [GlcCys], formed by the condensation reaction of β-d-glucose and l-cysteine, prevents the formation of its Pt(II) complexes. Differently, FruMet well reacts with K2PtCl4 in 1:1 M/L molar ratio leading to the formation of [Pt(FruMet-N,S)Cl2], in which the Amadori compound coordinates the metal ion through nitrogen and sulphur atoms. FruMet originates also a solid trans complex [Pt(FruMet-N,S)2]Cl2. Its NMR solution study allowed to identify two isomers with respect to nitrogen and sulphur atoms: R,R and S,S.In [Pt2FruCyscysCl4] species, FruCyscys molecule links two Pt(II) ions giving rise to two pentaatomic N,S-chelate rings.
1H, 13C, 195Pt NMR study on platinum(II) interaction with sulphur containing Amadori compounds is performed. The Amadori compounds are derived from the reaction of β-d-glucose with l-cystine leading to N,N′-di-(1-deoxy-β-fructos-1-yl)-l-cystine [FruCyscys], and with l-methionine leading to N-(1-deoxy-β-fructos-1-yl)-l-methionine [FruMet]. The reaction of FruMet with Pt(II) forms the trans complex [Pt(FruMet-N,S)2]Cl2.Figure optionsDownload as PowerPoint slide
Journal: Polyhedron - Volume 26, Issue 15, 20 September 2007, Pages 4045–4052