Photophysical behaviour of asymmetrically substituted metal free, Mg and Zn phthalocyanines in the presence of folic acid

This work reports on the synthesis, characterisation and photophysical properties of new asymmetric metal free, magnesium and zinc phthalocyanines containing a mono carboxylic acid group for possible linking to biological molecules via an amide bond. Successful synthesis of the phthalocyanines was achieved through the statistical condensation method. The phthalocyanines were mixed with folic acid and their photophysical properties were examined. The triplet quantum yield values for all the complexes in DMSO were between 0.49 and 0.74 and in the presence of folic acid they were between 0.37 and 0.63. The lifetimes were generally good ranging from 70 to 290 μs in the absence or presence of folic acid.

Asymmetric metal free, magnesium and zinc phthalocyanines containing a mono carboxylic acid group have been synthesised, the photophysical properties of the complexes are not affected by the presence of folic acid.Figure optionsDownload as PowerPoint slideResearch highlights
► Phthalocyanines containing mono carboxylic acid group for possible linking to biological molecules via an amide bond have been synthesised.
► The photophysical properties of the complexes are not affected by the presence of folic acid.
► The triplet quantum yield values of the complexes decreased in the presence of folic acid.
► The lifetimes were ranged from 70 to 290 μs in the absence or presence of folic acid.