New cadmium chloride complexes with imidazolidine-2-thione and its derivatives: X-ray structures, solid state and solution NMR and antimicrobial activity studies

Reactions of imidazolidine-2-thione (Imt), 1,3-diazinane-2-thione (Diaz) and 1,3-diazipane-2-thione (Diap) with cadmium(II) chloride in methanol result in the formation of 2:1 complexes. Both solid state and solution NMR, in addition to X-ray structures, confirm the exocyclic sulfur atom to be the donor in all cases. Cadmium shielding tensors and anisotropies were calculated from the solid-state NMR spectra. The X-ray structures of two complexes (NMeImt)2CdCl2 and (NEtImt)2CdCl2 reveal distorted tetrahedral geometries. Antimicrobial activity studies show that the Cd(Diap)2Cl2 complex exhibits substantial antibacterial activities compared to the corresponding Zn(II) complex.

Reactions of imidazolidine-2-thione (Imt), 1,3-diazinane-2-thione (Diaz) and 1,3-diazipane-2-thione (Diap) with cadmium(II) chloride in methanol result in the formation of 2:1 complexes. Both solid state and solution NMR, in addition to X-ray structures, confirm the exocyclic sulfur atom to be the donor in all cases. Cadmium shielding tensors and anisotropies were calculated from the solid-state NMR spectra. The X-ray structures of two complexes, (NMeImt)2CdCl2 and (NEtImt)2CdCl2, reveal distorted tetrahedral geometries. Antimicrobial activity studies show that the Cd(Diap)2Cl2 complex exhibits substantial antibacterial activities compared to the corresponding Zn(II) complex.Figure optionsDownload as PowerPoint slide