کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1339382 | 979704 | 2008 | 15 صفحه PDF | دانلود رایگان |
A series of half-sandwich ruthenium(II) complexes containing κ3(N,N,N)-hydridotris(pyrazolyl)borate (κ3(N,N,N)-Tp) and the water-soluble phosphane 1,3,5-triaza-7-phosphaadamantane (PTA) [RuX{κ3(N,N,N)-Tp}(PPh3)2−n(PTA)n] (n = 2, X = Cl (1), n = 1, X = Cl (2), I (3), NCS (4), H (5)) and [Ru{κ3(N,N,N)-Tp}(PPh3)(PTA)L][PF6] (L = NCMe (6), PTA (7)) have been synthesized. Complexes containing 1-methyl-3,5-diaza-1-azonia-7-phosphaadamantane(m-PTA) triflate [RuCl{κ3(N,N,N)-Tp}(m-PTA)2][CF3SO3]2 (8) and [RuX{κ3(N,N,N)-Tp}(PPh3)(m-PTA)][CF3SO3] (X = Cl (9), H (10)) have been obtained by treatment, respectively, of complexes 1, 2 and 5 with methyl triflate. Single crystal X-ray diffraction analysis for complexes 1, 2 and 4 have been carried out. DNA binding properties by using a mobility shift assay and antimicrobial activity of selected complexes have been evaluated.
A series of water-soluble ruthenium(II) complexes containing κ3(N,N,N)-hydridotris(pyrazolyl)borate (κ3(N,N,N)-Tp) and the water-soluble phosphanes 1,3,5-triaza-7-phosphaadamantane (PTA) and [1-methyl-3,5-diaza-1-azonia-7-phosphaadamantane (m-PTA) triflate have been synthesized. DNA binding properties by using a mobility shift assay as well as cytotoxicity against a variety of microorganisms have been evaluated.Figure optionsDownload as PowerPoint slide
Journal: Polyhedron - Volume 27, Issue 4, 15 March 2008, Pages 1214–1228