کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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1339475 | 979707 | 2010 | 8 صفحه PDF | دانلود رایگان |
A new chloride-dimethylsulfoxide-ruthenium(III) complex with nicotine trans-[RuIIICl4(DMSO)[H-(Nicotine)]] (1) and three related iridium(III) complexes; [H-(Nicotine)]trans-[IrIIICl4(DMSO)2] (2), trans-[IrIIICl4(DMSO)[H-(Nicotine)]] (3) and mer-[IrIIICl3(DMSO)(Nicotine)2] (4) have been synthesized and characterized by spectroscopic techniques and by single crystal X-ray diffraction (1, 2, and 4). Protonated nicotine at pyrrolidine nitrogen is present in complexes 1 and 3 while two neutral nicotine ligands are observed in 4. In these three inner-sphere complexes coordination occurs through the pyridine nitrogen. Moreover, in the outer-sphere complex 2, an electrostatic interaction is observed between a cationic protonated nicotine at the pyrrolidine nitrogen and the anionic trans-[IrIIICl4(DMSO)2]¯ complex.Electrophoretic mobility and atomic force microscopy (AFM) studies of the interaction between 1 and 3 complexes and plasmidic DNA pBR322 have been performed. These results show that the Ru(III) complex 1 interacts significantly with plasmidic DNA while a weak interaction is observed with the corresponding Ir(III) complex 3.
New chloride-dimethylsulfoxide-ruthenium(III) and iridium(III) complexes with nicotine trans-[RuIIICl4(DMSO)[H-(Nicotine)]] (1), [H-(Nicotine)]trans-[IrIIICl4(DMSO)2] (2), trans-[IrIIICl4(DMSO)[H-(Nicotine)]] (3), and mer-[IrIIICl3(DMSO)(Nicotine)2] (4) have been synthesized and characterized by spectroscopic and X-ray diffraction techniques (1, 2, and 4). Electrophoretic mobility and AFM studies of the interaction between 1 and 3 complexes and plasmidic DNA have been performed.Figure optionsDownload as PowerPoint slide
Journal: Polyhedron - Volume 29, Issue 1, 13 January 2010, Pages 34–41