کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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1340757 | 979752 | 2007 | 6 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: Selective fluorescence detection of nitroxyl over nitric oxide in buffered aqueous solution using a conjugated metallopolymer Selective fluorescence detection of nitroxyl over nitric oxide in buffered aqueous solution using a conjugated metallopolymer](/preview/png/1340757.png)
A bithiophene-substituted poly(p-phenyleneethynylene) derivative (CP1) having water-solubilizing side chains was prepared and characterized. Copper(II)-induced quenching of CP1 emission was quantified in H2O, MeCN/H2O (90:10), and pH 7.4, 50 mM HEPES, 100 mM KCl buffer. In buffer, treatment of CP1-Cu(II) with nitroxyl (HNO) produces an immediate 2.1-fold increase in emission, whereas exposure to NO(g) effects no fluorescence restoration. The ability to distinguish HNO from NO chemically at physiological pH represents a productive step towards the development of selective, fluorescence-based biosensors for HNO.
A bithiophene-substituted poly(p-phenyleneethynylene) derivative (CP1) having water-solubilizing side chains was prepared and characterized. Copper(II)-induced quenching of CP1 emission was quantified in H2O, MeCN/H2O, and pH 7.4 HEPES/KCl buffer. In buffer, treatment of CP1-Cu(II) with nitroxyl (HNO) produces an immediate 2.1-fold increase in emission, whereas exposure to NO(g) effects no fluorescence restoration.Figure optionsDownload as PowerPoint slide
Journal: Polyhedron - Volume 26, Issue 16, 10 October 2007, Pages 4625–4630