Iridoids, flavonoids, and monoterpene diglycoside from the roots of Triosteum himalayanum Wall.

• Sixteen compounds were isolated from the roots of Triosteum himalayanum Wall.
• Two iridoid glucosides (1 and 2) are new compounds.
• Compounds 9–16 were isolated from the genus Triosteum for the first time.

The phytochemical investigation of the roots of Triosteum himalayanum Wall. led to the isolation of eleven iridoids (1–6 and 8–12), one monoterpene diglycoside (7), and four flavonoids (13–16), of which 4′,6′-di-O-isopropylidene sweroside (1) and secologanin diethylacetal (2) were new iridoid glucosides. The existence of iridoids and flavonoids provided further confirmation of the typical profile of the secondary metabolites found in the genus Triosteum, suggesting a close relationship among the species of Caprifoliaceae.

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