Chemistry for oncotheranostic gold nanoparticles

• A didactic survey of gold nanoparticles synthesis.
• Anticancer agents and targeting strategy used with gold nanoparticles are shortly presented.
• The parameters for gold nanoparticles biodistribution are described.
• Chemicals used to functionalize gold nanoparticles are reviewed by classes.
• Principle for bioassays in oncology involving gold nanoparticles are presented.

This review presents in a comprehensive ways the chemical methods used to functionalize gold nanoparticles with focus on anti-cancer applications. The review covers the parameters required for the synthesis gold nanoparticles with defined shapes and sizes, method for targeted delivery in tumours, and selected examples of anti-cancers compounds delivered with gold nanoparticles. A short survey of bioassays for oncology based on gold nanoparticles is also presented.

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