کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1393259 1501195 2009 10 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Synthesis, antimicrobial and antioxidant activities of substituted pyrazoles, isoxazoles, pyrimidine and thioxopyrimidine derivatives
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آلی
پیش نمایش صفحه اول مقاله
Synthesis, antimicrobial and antioxidant activities of substituted pyrazoles, isoxazoles, pyrimidine and thioxopyrimidine derivatives
چکیده انگلیسی

A new class of heterocycles, substituted pyrazoles, isoxazoles, pyrimidines, thioxopyrimidines were prepared from Michael adducts, 2-(1,2-diaroylethyl)malononitrile and 2-(1,2-diarylsulfonylethyl)malononitrile by cyclocondensation with appropriate nucleophiles. The lead compounds were screened for the antimicrobial and antioxidant activities.

A new class of heterocycles, substituted pyrazoles, isoxazoles, pyrimidines, thioxopyrimidines were prepared from Michael adducts, 2-(1,2-diaroylethyl)malononitrile and 2-(1,2-diarylsulfonylethyl)malononitrile by cyclocondensation with appropriate nucleophiles. The lead compounds were screened for the antimicrobial and antioxidant activities.Figure optionsDownload as PowerPoint slide

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: European Journal of Medicinal Chemistry - Volume 44, Issue 11, November 2009, Pages 4557–4566
نویسندگان
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