کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1394157 1501138 2014 35 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Chromones as a privileged scaffold in drug discovery: A review
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آلی
پیش نمایش صفحه اول مقاله
Chromones as a privileged scaffold in drug discovery: A review
چکیده انگلیسی


• A brief outline on the structure of chromone and its isomers.
• A comprehensive collection of biologically active derivatives of chromone.
• This article focuses on the pharmacological profile of chromone derivatives in the current literature.
• Role of chromone in the management by targeting various receptor sites.

The chromone and its derivatives are the most important heterocyclic compounds, which is a common and integral feature of a variety of natural products and medicinal agents. These heterocycles show a variety of pharmacological properties, and change of their structure offers a high degree of diversity that has proven useful for the search of new therapeutic agents. A large volume of research has been carried out on chromone and their derivatives, which has proved the pharmacological importance of this heterocyclic nucleus. The present review focuses on the pharmacological profile of chromone derivatives in the current literature with an update of recent research findings on this nucleus and the perspectives that they hold for future research.

The present review focuses on the pharmacological profile of chromone derivatives in the current literature with an update of recent research and the perspectives that they hold for future research. Figure optionsDownload as PowerPoint slide

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: European Journal of Medicinal Chemistry - Volume 78, 6 May 2014, Pages 340–374
نویسندگان
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