Molecular iodine promoted synthesis of new pyrazolo[3,4-d]pyrimidine derivatives as potential antibacterial agents

Iodocyclization of 5-amino-1-(2,4-dinitrophenyl)-1H-4-pyrazolcarboxamides with aromatic aldehydes gave a new series of pyrazolo[3,4-d]pyrimidine derivatives in a single step and their antibacterial activity comparable to Streptomycin as reference drug was evaluated.

A new series of pyrazolo[3,4-d]pyrimidine derivatives have been synthesized and tested for their antibacterial effects.Figure optionsDownload as PowerPoint slide