کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1396291 | 1501183 | 2010 | 5 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Synthesis and antituberculosis activity of some new pyridazine derivatives. Part II
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موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آلی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Synthesis and antituberculosis activity of some new pyridazine derivatives. Part II Synthesis and antituberculosis activity of some new pyridazine derivatives. Part II](/preview/png/1396291.png)
چکیده انگلیسی
A series of eighteen novel compounds with pyridazine moiety were synthesized and their in vitro antituberculosis activities have been evaluated. A fast, general, and facile method for preparation of pyridazine derivatives in moderate to excellent yields is presented. Three compounds were found to be moderate active against Mycobacterium tuberculosis. Correlation of structure–biological activity has been done.
Synthesis, structure and in vitro antituberculosis activity of some new pyridazine derivatives are described.Figure optionsDownload as PowerPoint slide
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: European Journal of Medicinal Chemistry - Volume 45, Issue 11, November 2010, Pages 5164–5168
Journal: European Journal of Medicinal Chemistry - Volume 45, Issue 11, November 2010, Pages 5164–5168
نویسندگان
Dorina Mantu, Mihaela Cătălina Luca, Costel Moldoveanu, Gheorghita Zbancioc, Ionel I. Mangalagiu,